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fth1  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc fth1
    Fth1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 379 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+fth1/FTH1+Rabbit+mAb/pmc12933830-167-3-4
    Average 96 stars, based on 379 article reviews
    fth1 - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    other:

    Article Title: Transdermal siRNA delivery via biomineralized nanoparticle-incorporated microneedles modulates cuproptosis-ferroptosis interaction for psoriasis therapy.
    Article Snippet: SimpleChIP® Enzymatic Chromatin IP Kit (Magnetic Beads) and antibody against FTH1, H3K4me3 and H3 were obtained from Cell Signaling Technology, lnc. (Danvers, MA, USA).

    Article Title: Ferroptosis modulation by Toxoplasma gondii suppresses sodium iodate-driven age-related macular degeneration.
    Article Snippet: Retinal degeneration is a major cause of irreversible visual impairment, in which oxidative stress plays a critical role by promoting injury and death of retinal pigment epithelium (RPE) cells (Datta et al. 2017).. Based on that knowledge, sodium iodate (NaIO3) is widely used to induce oxidative stress–mediated RPE damage, providing a well-established experimental model for studying retinal degenerative diseases (Hanus et al. 2016).. NaIO3 exposure has been known to disrupt mitochondrial function and redox homeostasis, leading to excessive reactive oxygen species (ROS) accumulation and dysregulated iron metabolism (Liu et al. 2021).

    Article Title: DPP4-regulated endothelial cell ferroptosis modulates atherosclerosis progression by ferritinophagy.
    Article Snippet: Background: Atherosclerosis (AS), the primary pathophysiological foundation of coronary artery disease (CAD), initiates through endothelial dysfunction that facilitates lipid deposition and plaque formation.. Emerging evidence implicates dipeptidyl peptidase IV (DPP4) in vascular pathologies, yet its mechanistic role in AS-associated endothelial ferroptosis remains undefined.. Methods: Multidisciplinary approaches were employed: 1) Bioinformatic analysis of public databases identified DPP4-ferroptosis-AS associations; 2) Clinical samples measured plasma DPP4 levels across CAD severity strata; 3) Atherogenic progression was compared between DPP4 /− ApoE /− and ApoE /− mice under a high-fat diet; 4) Ox-LDL-induced endothelial injury models assessed DPP4-mediated ferroptosis mechanisms combining proteomics, cycloheximide chase assays, and pharmacological modulation of autophagy.

    Article Title: Transdermal siRNA delivery via biomineralized nanoparticle-incorporated microneedles modulates cuproptosis-ferroptosis interaction for psoriasis therapy
    Article Snippet: SimpleChIP® Enzymatic Chromatin IP Kit (Magnetic Beads) and antibody against FTH1, H3K4me3 and H3 were obtained from Cell Signaling Technology, lnc. (Danvers, MA, USA).

    Western Blot:

    Article Title: NCOA4-Mediated Ferritinophagy Induces Ferroptosis and Enriches Ferritin-Containing EVs via Ferritin Phase Separation to Promote Mechanical Ventilation-Induced Pulmonary Fibrosis
    Article Snippet: Following three washes with 1 × TBST, membranes were then probed with HRP-conjugated secondary antibodies diluted 1:4000 at room temperature for 1 h. Blots were visualized using Image Lab TM software (Biorad, USA) with the enhanced chemiluminescence (ECL) system (Vazyme, China). .. The primary antibodies used for immunoblotting included anti-Fibronectin (ab268020, Abcam, USA), anti-alpha smooth muscle Actin (ab5694, Abcam, USA), anti-β-tubulin (HRP-66240, Proteintech, China), anti-GPX4 (ab125066, Abcam, USA), anti-SLC7A11 (ab307601, Abcam, USA), anti-FTH1 (4393S, CST, USA), anti-Alix (ab186429, Abcam, USA), anti-CD63 (ab217345, Abcam, USA), anti-NCOA4 (PA5-96398, Thermofisher, USA), anti-AGTR1 (NBP1-77078, Novus Biologicals, USA), and anti-Angiotensin II (ab259823, Abcam, USA). .. The HRP-conjugated secondary antibodies used included Anti-rabbit IgG (A0208, Beyotime, China) and Anti-mouse IgG (A0216, Beyotime, China).



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